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Dong-Kug Choi Selected Research

1-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)

4/2022Dioscin-Mediated Autophagy Alleviates MPP+-Induced Neuronal Degeneration: An In Vitro Parkinson's Disease Model.
10/2020GPR4 Knockout Improves the Neurotoxin-Induced, Caspase-Dependent Mitochondrial Apoptosis of the Dopaminergic Neuronal Cell.
2/2017Analysis of Epidermal Growth Factor Receptor Related Gene Expression Changes in a Cellular and Animal Model of Parkinson's Disease.
1/2013Gastrodin protects apoptotic dopaminergic neurons in a toxin-induced Parkinson's disease model.
6/2011Neuroprotective effects of vanillyl alcohol in Gastrodia elata Blume through suppression of oxidative stress and anti-apoptotic activity in toxin-induced dopaminergic MN9D cells.
1/2011A novel synthetic compound PHID (8-Phenyl-6a, 7, 8, 9, 9a, 10-hexahydro-6H-isoindolo [5, 6-g] quinoxaline-7, 9-dione) protects SH-SY5Y cells against MPP(+)-induced cytotoxicity through inhibition of reactive oxygen species generation and JNK signaling.

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Dong-Kug Choi Research Topics

Disease

34Parkinson Disease (Parkinson's Disease)
04/2022 - 03/2002
28Neuroinflammatory Diseases
01/2022 - 08/2006
17Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022 - 03/2002
13Inflammation (Inflammations)
01/2021 - 04/2003
8Cognitive Dysfunction
05/2021 - 01/2012
7Neuroblastoma
04/2022 - 06/2003
6Mitochondrial Diseases (Mitochondrial Disease)
01/2022 - 01/2012
5Neoplasms (Cancer)
10/2020 - 09/2002
4Nervous System Diseases (Neurological Disorders)
01/2022 - 01/2018
4Alzheimer Disease (Alzheimer's Disease)
01/2022 - 09/2016
4Chronic Disease (Chronic Diseases)
01/2018 - 01/2014
3Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2021 - 04/2005
3Hypoxia (Hypoxemia)
01/2016 - 01/2015
3Gliosis
08/2013 - 04/2005
2B-Cell Lymphoma (Lymphoma, B Cell)
04/2022 - 10/2020
2Epilepsy (Aura)
01/2022 - 01/2019
2Amnesia (Dissociative Amnesia)
05/2021 - 08/2017
2Huntington Disease (Huntington's Disease)
01/2021 - 01/2005
2Wounds and Injuries (Trauma)
01/2019 - 01/2018
2Brain Diseases (Brain Disorder)
01/2018 - 12/2016
2Pain (Aches)
04/2015 - 01/2013
2Hypokinesia (Bradykinesia)
04/2015 - 01/2013
2Adenocarcinoma
10/2002 - 09/2002
1Genomic Instability
01/2021
1Pathologic Processes
01/2021
1Memory Disorders (Memory Loss)
01/2021
1Diabetic Neuropathies (Diabetic Neuropathy)
01/2019
1Stroke (Strokes)
01/2019
1Infections
01/2018
1Obesity
01/2018
1Cicatrix (Scar)
01/2017

Drug/Important Bio-Agent (IBA)

151- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
04/2021 - 03/2002
11Proteins (Proteins, Gene)FDA Link
01/2022 - 05/2007
9CytokinesIBA
01/2021 - 01/2012
7NeurotoxinsIBA
09/2016 - 04/2003
61-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)IBA
04/2022 - 01/2011
6Pharmaceutical PreparationsIBA
01/2022 - 09/2016
6AntioxidantsIBA
01/2021 - 01/2012
6Biological ProductsIBA
01/2021 - 01/2014
5Neuroprotective AgentsIBA
01/2022 - 01/2005
5asaroneIBA
01/2022 - 01/2012
5Dopamine (Intropin)FDA LinkGeneric
01/2021 - 01/2012
4Scopolamine (Hyoscine)FDA Link
05/2021 - 08/2017
4LipopolysaccharidesIBA
05/2021 - 04/2011
4Cholinergic Agents (Cholinergics)IBA
07/2019 - 01/2012
4NF-kappa B (NF-kB)IBA
01/2017 - 05/2010
3Caspase 3 (Caspase-3)IBA
04/2022 - 12/2009
3SynucleinsIBA
01/2022 - 01/2012
3Oxygen (Dioxygen)IBA
01/2016 - 01/2015
3Transcription Factors (Transcription Factor)IBA
06/2015 - 12/2012
3Free RadicalsIBA
09/2012 - 01/2003
3Reactive Oxygen Species (Oxygen Radicals)IBA
03/2012 - 01/2011
3Cyclooxygenase 2 (Cyclooxygenase-2)IBA
10/2009 - 04/2003
2Nerve Growth Factors (Neurotrophins)IBA
01/2022 - 01/2021
2CaspasesIBA
04/2021 - 01/2021
2Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
01/2021 - 01/2018
2PhytochemicalsIBA
01/2021 - 01/2018
2RotenoneIBA
01/2021 - 08/2011
2gintoninIBA
01/2021 - 09/2018
2LipidsIBA
01/2020 - 10/2018
2Lipid NanoparticlesIBA
03/2019 - 01/2018
2TaurineFDA Link
01/2019 - 01/2015
2IronIBA
01/2016 - 01/2012
2CannabinoidsIBA
04/2015 - 01/2013
2Nitric Oxide (Nitrogen Monoxide)FDA Link
06/2014 - 01/2003
2Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
03/2012 - 12/2009
2EnzymesIBA
01/2012 - 07/2005
2DNA (Deoxyribonucleic Acid)IBA
10/2009 - 08/2007
2OsteonectinIBA
10/2002 - 09/2002
1dioscinIBA
04/2022
1Vesicular Monoamine Transport Proteins (Vesicular Monoamine Transporter)IBA
01/2021
14-trifluoromethylsalicylic acid (HTB)IBA
11/2020
1AnhydridesIBA
11/2020
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
10/2020
1Messenger RNA (mRNA)IBA
10/2020
1bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA
10/2020
1Complement System Proteins (Complement)IBA
10/2020
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2020
1InflammasomesIBA
01/2020
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
10/2019
1QuercetinIBA
10/2019
1GTP-Binding Proteins (G-Protein)IBA
10/2019
1CurcuminIBA
03/2019
1PolyphenolsIBA
01/2019
1Toll-Like Receptors (Toll-Like Receptor)IBA
01/2019
1irilin BIBA
01/2019
1ChemokinesIBA
10/2018
1GinsenosidesIBA
09/2018
1Liposomes (Liposome)IBA
09/2018
1ginsenoside M1IBA
09/2018
1Glutamate Receptors (Glutamate Receptor)IBA
01/2018
1thymoquinoneIBA
01/2018
1Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2018
1Coloring Agents (Dyes)IBA
01/2018
1atractylenolide IIBA
05/2017
1ErbB Receptors (EGF Receptor)IBA
02/2017
1Retinaldehyde (Retinal)IBA
01/2017

Therapy/Procedure

8Therapeutics
04/2022 - 04/2015
2Oral Administration
11/2020 - 07/2019
2East Asian Traditional Medicine (Oriental Medicine)
04/2015 - 11/2013